According to Wikipedia: Native Americans, using dugout canoes to navigate the waterways, hunted and camped in Georgia's coastal islands for thousands of years. The Euchee tribe likely inhabited Tybee Island in the years preceding the arrival of the first Spanish explorers in the area in the 16th century. "Tybee" is the Euchee word for "salt."
Wikipedia also says that pirates used the island to hide from those who pursued them. Nowadays ordinary folk go there to hide from hustles and bustles. That's exactly why we recently bought a home away from home smack dab in the middle of Tybee Island, Georgia, our favorite suburb of heaven.